"How to Save a Life" is a song by the American rock band The Fray, written and performed in the key of B major. It was released as the second single from their debut studio album of the same name in 2005. The song was composed by the band members Isaac Slade and Joe King, and its lyrics touch upon themes of loss, regret, and reaching out to help someone in need. The track gained significant popularity and acclaim, reaching the top three on the Billboard Hot 100 chart and becoming a commercial success worldwide. Notably, "How to Save a Life" was also used as the title track for an episode of the popular medical drama Grey's Anatomy, further boosting its exposure and popularity. The melody of the song is characterized by emotive piano and guitar accompaniment, complementing Slade's heartfelt vocals.
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